Current humans originated in Africa some 200,000 years ago, and it was only during 10,000 years that humans were able to start developing their civilisations.
My assumption is humans repeated incest for more than the rest of 190,000 years and it was only Adam that noticed their practice might bring some inconvenience. Genetic disorder must be the result of practicing incest too many years. Adam must have noticed mating to other family prevents from this gene defects.
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